If youll remember, Scotland just went thru an independence vote of its own a year and a half ago. The vote did not pass (about 3% more votes to remain); however, one of the stipulations for remaining with no further referendum was that Great Britain remain part of the EU. It was also one of the major arguing points of the Remain campaign, ie "You wont be able to just willy nilly join the EU upon independence" which is/was technically true.
So now a year and a half later Scotland, as it exists as part of the United Kingdom, voted to remain part of the EU as they were promised and Great Britain up and decided to leave anyway.
So a new referendum is bound to come. If they were smart, they wait a year or two to see how things shake out. If a lot of the economists (and Bruiser) are right, then the Kingdom wont be so United any longer.
On top, Sinn Fein is calling for a North Irish referendum. If that goes thru, which it might, and there is a vote, the chances of North Ireland leaving the United Kingdom are far greater than the past Scottish vote, Id wager.